---
title: >-
  Real-world evidence on atopic dermatitis: Baseline characteristics and
  predictors of treatment choice in the TARGET cohort.
description: >-
  Explore this publication on real-world evidence: Real-world evidence on atopic
  dermatitis: Baseline characteristics and predictors of treatment choice in
  the…
date: '2022-01-01'
category: Publications
tags:
  - Journal Of The American Academy Of Dermatology
  - Abstract / Manuscript
  - Approval / Commercialization
  - Care
  - Dermatology
  - Atopic Dermatitis (AD)
  - Health System Partner
canonical_url: >-
  https://www.pedestalhealth.com/resources/publications/journal-of-the-american-academy-of-dermatology/real-world-evidence-on-atopic-dermatitis-baseline/
source: Pedestal Health
license: © 2026 Pedestal Health. All rights reserved.
slug: real-world-evidence-on-atopic-dermatitis-baseline
id: 6M1HKe61aEamPoMYb6cmat
contentType: article
---

## Challenge

Drug development for advanced AD therapies required a real-world baseline understanding of which patient characteristics—clinical, demographic, and insurance-related—predicted advanced systemic therapy initiation versus remaining on conventional treatments, to inform trial enrollment design and commercial access strategy.

## Solution

The TARGET-DERM AD cohort was analyzed to describe baseline characteristics and identify independent predictors of advanced systemic therapy initiation using multivariable logistic regression, providing the first large-scale real-world characterization of the AD treatment decision landscape in the US.

## Impact

Establishing that disease severity, insurance type, and site of care independently predict AST initiation identifies actionable access barriers and informs trial site selection, enrollment enrichment, and health equity strategies for AD drug development programs.

### [Julie M. Crawford](/people/julie-crawford/)

### [Breda Munoz](/people/breda-munoz/)

![Breda Munoz, PhD — Profile Photo](https://images.ctfassets.net/h4s3ip99qawo/3H1T2mfvSNFj6w9tulnreq/a74ae05fe53e400f176d4e9c617b8fb8/breda-munoz.jpg)