---
title: Use of tenofovir-based PrEP among pregnant women in South Africa.
description: >-
  Explore this publication on real-world evidence: Use of tenofovir-based PrEP
  among pregnant women in South Africa..
date: '2024-01-01'
category: Publications
tags:
  - Aids
  - Abstract / Manuscript
  - R&D
  - Care
  - Methods/Pharmacoepi
  - HIV
  - Health System Partner
canonical_url: >-
  https://www.pedestalhealth.com/resources/publications/aids/use-of-tenofovir-based-prep-among-pregnant-women-in-south/
source: Pedestal Health
license: © 2026 Pedestal Health. All rights reserved.
slug: use-of-tenofovir-based-prep-among-pregnant-women-in-south
id: 2BZQsZcSHI5Sm6Cb29kTXd
contentType: article
---

## Challenge

The safety of tenofovir-based PrEP during pregnancy is critically important for HIV prevention in South Africa, but real-world data on PrEP use patterns specifically during pregnancy had not been characterized in this population.

## Solution

Target RWE's HIV team analyzed real-world data from South African women to characterize patterns of tenofovir-based PrEP use during pregnancy, including initiation, continuation, and discontinuation relative to gestational periods.

## Impact

Documenting real-world PrEP use patterns during pregnancy in high-HIV-incidence South African women provides evidence for HIV prevention program design and adherence interventions targeting pregnant and periconception women.