---
title: >-
  Burden of Disease is Positively Associated with Disease Severity in Atopic
  Dermatitis
description: >-
  Explore this publication on real-world evidence: Burden of Disease is
  Positively Associated with Disease Severity in Atopic Dermatitis..
date: '2022-01-01'
category: Publications
tags:
  - Care
  - Atopic Dermatitis (AD)
  - Health System Partner
  - Pharma Partner
  - Poster Presentation
  - R&D
  - RAD Conference
  - Dermatology
canonical_url: >-
  https://www.pedestalhealth.com/resources/publications/care/burden-of-disease-is-positively-associated-with-disease/
source: Pedestal Health
license: © 2026 Pedestal Health. All rights reserved.
slug: burden-of-disease-is-positively-associated-with-disease
id: 3Yj09UBmBXVhbotlmtqZOd
contentType: article
---

## Challenge

This is a Fall Clinical 2022 poster version of the same burden-by-severity study as Row 11 (manuscript) and Row 40 (RAD 2021 poster). Conference presentation of the finding that vIGA-AD severity is strongly associated with patient-reported symptom and QoL burden.

## Solution

TARGET-DERM AD cohort analysis examining associations between vIGA-AD severity categories and POEM/DLQI/CDLQI using ordinal logistic and linear regression.

## Impact

Fall Clinical 2022 dissemination of the vIGA-AD/PRO correlation evidence broadens prescriber and sponsor awareness of the clinical meaningfulness of disease severity assessment, supporting PRO endpoint adoption in AD trials.

### [Breda Munoz](/people/breda-munoz/)

![Breda Munoz, PhD — Profile Photo](https://images.ctfassets.net/h4s3ip99qawo/3H1T2mfvSNFj6w9tulnreq/a74ae05fe53e400f176d4e9c617b8fb8/breda-munoz.jpg)

Breda Munoz, PhD, is a senior statistician at Target RWE with more than 17 years of experience on applied and methodological studies in epidemiological, biological, public health and social sciences. Prior to Target RWE, Dr. Munoz worked 15 years in RTI International as a senior statistician in a variety of research projects.



### [Julie M. Crawford](/people/julie-crawford/)