---
title: >-
  Demographics and disease characteristics of patients with alopecia areata with
  comorbid atopic dermatitis, vitiligo or anxiety/depression: TARGET-DERM AA.
description: >-
  Explore this publication on real-world evidence: Demographics and disease
  characteristics of patients with alopecia areata with comorbid atopic
  dermatitis,…
date: '2024-01-01'
category: Publications
tags:
  - Poster Presentation
  - R&D
  - Care
  - Dermatology
  - Alopecia Areata (AA)
  - Health System Partner
canonical_url: >-
  https://www.pedestalhealth.com/resources/publications/poster-presentation/demographics-and-disease-characteristics-of-patients-with/
source: Pedestal Health
license: © 2026 Pedestal Health. All rights reserved.
slug: demographics-and-disease-characteristics-of-patients-with
id: 4gQabrfATXnBWxTm7sia0M
contentType: article
---

## Challenge

AA frequently co-occurs with AD, vitiligo, anxiety, and depression, but the specific impact of these comorbidities on AA disease severity and patient-reported burden had not been characterized in a large real-world North American registry, limiting the design of comorbidity-aware trials and holistic treatment assessments.

## Solution

The TARGET-DERM AA registry was used to characterize demographics, SALT severity, and patient-reported anxiety, depression, and AAPPO outcomes across AA patients with and without comorbid AD, vitiligo, and anxiety/depression.

## Impact

Establishing that anxiety and depression are highly prevalent in AA—particularly in adults—and are associated with worse patient-reported disease experience provides evidence for psychiatric endpoints in AA trials and supports the value of holistic treatment effects beyond scalp hair regrowth in regulatory and payer contexts.

### [Julie M. Crawford](/people/julie-crawford/)

### [Breda Munoz](/people/breda-munoz/)

![Breda Munoz, PhD — Profile Photo](https://images.ctfassets.net/h4s3ip99qawo/3H1T2mfvSNFj6w9tulnreq/a74ae05fe53e400f176d4e9c617b8fb8/breda-munoz.jpg)