---
title: >-
  Real world treatment patterns and outcomes for hepatocellular carcinoma (HCC)
  patients receiving transarterial chemoembolization (TACE) or transarterial
  radioembolization (TARE) in the TARGET-HCC registry.
description: >-
  Explore this publication on real-world evidence: Real world treatment patterns
  and outcomes for hepatocellular carcinoma (HCC) patients receiving…
date: '2025-01-01'
category: Publications
tags:
  - EASL Congress
  - Poster Presentation
  - Approval / Commercialization
  - Care
  - Hepatology
  - HCC
  - Pharma Partner
canonical_url: >-
  https://www.pedestalhealth.com/resources/publications/easl-congress/real-world-treatment-patterns-and-outcomes-for/
source: Pedestal Health
license: © 2026 Pedestal Health. All rights reserved.
slug: real-world-treatment-patterns-and-outcomes-for
id: hCEu7rp7GeKESlNAgS19V
contentType: article
---

## Challenge

Intermediate-stage HCC patients receiving TACE or TARE represent a large and heterogeneous population, but real-world data on response patterns, suitability for re-treatment, and subsequent treatment sequences—particularly the transition to systemic therapy—were lacking, limiting treatment sequencing guidance.

## Solution

The TARGET-HCC registry was used to analyze response to first and second rounds of TACE or TARE, TACE/TARE unsuitability rates after each round, treatment sequences following locoregional therapy, and overall survival stratified by response pattern in a retrospective cohort study.

## Impact

Demonstrating that two-thirds of patients become unsuitable for continued TACE or TARE after a first round—yet fewer than a quarter receive subsequent systemic therapy—identifies a significant treatment gap and informs the evidence base for sequencing locoregional therapy with systemic agents in HCC.

### [Heather L. Morris](/people/heather-morris/)

![Heather Morris, PhD — Profile Photo](https://images.ctfassets.net/h4s3ip99qawo/16PnQ817q7tv964vhcUD5f/ce6797c32df11f022ef12ecbb9ffea49/heather-morris.jpg)

### [Andrea R. Mospan](/people/andrea-mospan/)

![Andrea R. Mospan, PhD, RAC — Profile Photo](https://images.ctfassets.net/h4s3ip99qawo/4w6bkwPHPqrXKYs4tHZPkK/1d21763b54ecc3466764986693b7072f/andrea-mospan.jpg)

### [Breda Munoz](/people/breda-munoz/)

![Breda Munoz, PhD — Profile Photo](https://images.ctfassets.net/h4s3ip99qawo/3H1T2mfvSNFj6w9tulnreq/a74ae05fe53e400f176d4e9c617b8fb8/breda-munoz.jpg)