---
title: >-
  The Pervasive Impact of Pruritus on Quality of Life in Patients with Primary
  Biliary Cholangitis (PBC): Real World Experience in TARGET-PBC
description: >-
  Explore this publication on real-world evidence: The Pervasive Impact of
  Pruritus on Quality of Life in Patients with Primary Biliary Cholangitis
  (PBC): Real…
date: '2020-01-01'
category: Publications
tags:
  - AASLD
  - Approval & Commercialization
  - Care
  - PBC
  - Health System Partner
  - Pharma Partner
  - Poster Presentation
  - Hepatology
canonical_url: >-
  https://www.pedestalhealth.com/resources/publications/aasld/the-pervasive-impact-of-pruritus-on-quality-of--2020-aasld/
source: Pedestal Health
license: © 2026 Pedestal Health. All rights reserved.
slug: the-pervasive-impact-of-pruritus-on-quality-of--2020-aasld
id: 7ERwQhciuCGsJTXI7uUS7E
contentType: article
---

## Challenge

This is a second conference presentation of the same pruritus impact study (presented as both AASLD 2020 posters 1276 and a companion publication), providing an additional dissemination venue for the multi-domain quality of life findings in PBC pruritus.

## Solution

Identical analytical approach to poster 61 above: TARGET-PBC PRO data analyzed across itch severity groups using PBC-40, 5D-Itch, and PROMIS Fatigue instruments.

## Impact

Multi-venue dissemination of the pruritus burden findings broadens the reach of the evidence to diverse clinical and scientific audiences, reinforcing the evidence base for anti-pruritic endpoints across gastroenterology and hepatology communities.

## Use Cases / Links

Multi-venue dissemination of PBC pruritus burden evidence for broad regulatory and clinical impact, PRO-based quality of life data in PBC pruritus for anti-pruritic drug development context, Patient burden evidence supporting GSK-TARGET partnership in PBC pruritus management