High PrEP uptake and objective longitudinal adherence among HIV-exposed women with personal or partner plans for pregnancy in rural Uganda: A cohort study

High PrEP uptake had been observed in controlled settings, but whether women with personal or partner HIV risk would achieve high objective adherence to daily oral TDF/FTC PrEP in real-world periconception settings remained unknown.

Target RWE's HIV team analyzed longitudinal PrEP uptake and objective adherence data from HIV-exposed South African women with personal or partner HIV risk planning for pregnancy.

Demonstrating high PrEP uptake and objective adherence among motivated periconception women provides evidence that real-world PrEP effectiveness is achievable, informing HIV prevention program scaling strategies.

PrEP uptake and objective adherence evidence in periconception South African women for HIV prevention program scaling, HIV prevention evidence supporting PrEP program design for periconception women