The Pervasive Impact of Pruritus on Quality of Life in Patients with Primary Biliary Cholangitis (PBC): Real World Experience in TARGET-PBC

Challenge

This is a second conference presentation of the same pruritus impact study (presented as both AASLD 2020 posters 1276 and a companion publication), providing an additional dissemination venue for the multi-domain quality of life findings in PBC pruritus.

Solution

Identical analytical approach to poster 61 above: TARGET-PBC PRO data analyzed across itch severity groups using PBC-40, 5D-Itch, and PROMIS Fatigue instruments.

Impact

Multi-venue dissemination of the pruritus burden findings broadens the reach of the evidence to diverse clinical and scientific audiences, reinforcing the evidence base for anti-pruritic endpoints across gastroenterology and hepatology communities.