Making complex treatment patterns legible.
Immunocompromised patients face higher risks from COVID-19, and treatment patterns in this group have been under-explored. Understanding how care varies is a first step toward consistency.
This poster describes treatment patterns and remdesivir use in the first days of hospitalization across US regions and variant eras, using UpSet plots to make complex therapy combinations readable. It is descriptive work, developed with co-authors from Gilead.
Descriptive treatment-pattern study
HealthVerity hospital data
UpSet-plot visualization
Citation
Hendrickson K, Rathnayaka N, Berry M, Nielson C, Brookhart A, Hurwitz K. Regional and variant era variation in treatment patterns and remdesivir use among immunocompromised patients hospitalized with COVID-19: an analysis of polypharmacy using UpSet plots. Poster C-123, 42nd ISPE Annual Meeting; August 29–September 2, 2026; Milan, Italy.

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